Type 2 Diabetes

Diabetes Type 2 belongs to the same classification of disease as Type 1. Type 2 Diabetes is typically characterized by insulin resistance, rather than depleted insulin production or secretion. The pancreas produces insulin, however the cells are resistant to the insulin, and as a result the cells are unable to breakdown glucose for energy. Type 2 diabetes is typically seen in people over 40 years of age, but can occur in anyone at any time. Unlike Type 1 diabetes, Ketoacidosis does not commonly occur in Type 2 diabetes; however it is not unknown. Other common symptoms may occur including severe joint pain, unhealing sores, and even a sense of increased aging. Type 2 Diabetes is typically onset. It is obtained as a result of years of metabolic abuse through unhealthy lifestyles and eating habits. If untreated, both Type 1 and Type 2 diabetes can lead to the failure of large organ systems, most commonly the cardiovascular, and will eventually result in death.

This diagram shows pre-diabetes symptoms

diabetes1.jpg

How Type 2 Diabetes works: on a molceular level

To understand type 2 diabetes, first you must understand how glucose is normally processed. Glucose is the prominent source of energy for the cells that make up your muscles and other tissues. Glucose comes from two major places: the food you eat and your liver. During digestion, sugar is absorbed into the bloodstream. It then usually, with the help of insulin, enters the cells. The hormone insulin comes from the pancreas. When you eat, your pancreas secretes insulin into your bloodstream. As insulin circulates, it acts like a key by unlocking microscopic doors that allow sugar to enter your cells. Insulin lowers the amount of sugar in your bloodstream. As your blood sugar level drops, so does the secretion of insulin from your pancreas. Your liver acts as a glucose factory and warehouse. When your insulin levels are low, such as when you don't eat for a while, your liver releases the stored glucose to keep your glucose level within a normal range. In type 2 diabetes, this process works improperly. Instead of moving into your cells, sugar builds up in your bloodstream. This occurs when your pancreas doesn't make enough insulin or your cells become resistant to the action of insulin. Exactly why this happens is uncertain, although excess fat — especially abdominal fat — and inactivity seem to be important factors. One solution to this seems to be a Gastric-Bypass surgery, or in certain cases a Mini-Gastric-Bypass surgery. Though these surgeries do not eliminate the disorder, they greatly aid in management and treatment of Type 2 Diabetes

Here's some information from an expert on metabolic diseases:


Diabetes Information Video

For more information on Type 2 Diabetes visit these web sites

diabetes.com

wikipedia.org

Diabetes.org